Journal of the American Medical Association · 1939 · 33 citations · 6 references
MedicineInfectious DiseasesOphthalmologyOcular DiseaseOcular PathologyOcular PharmacologyBacterial Eye InfectionsInfectious Eye DiseaseOcular Antimicrobial TherapyRabbit OphthalmologyAntibiotic Ophthalmic TherapyEye Infection ManagementGonococcal OphthalmiaHerpetic Corneal UlcerIntraocular Antibiotic TherapyStreptococcal Eye Infections
The widespread success enjoyed by sulfanilamide and its derivatives in the treatment of some infectious diseases has naturally called attention to possible applications in ophthalmology. Encouraging reports have already appeared in their use in trachoma by Kirk and his associates,<sup>1</sup>Loe<sup>2</sup>and others; in gonorrheal ophthalmia by Magitot and his associates,<sup>3</sup>Luis and Ricardo, Fernandez,<sup>4</sup>Willis<sup>5</sup>and others; in orbital cellulitis by Goldenburg<sup>6</sup>and Szinegh;<sup>7</sup>in abscess of the lid by Szinegh, and in herpetic corneal lesions by Kleefeld.<sup>8</sup>Experimentally, streptococcic infections in rabbits' eyes have been successfully treated with sulfanilamide by Rambo.<sup>9</sup>Little work has been done, however, on the penetration of this compound into the eye, although Marshall and his co-workers<sup>10</sup>demonstrated that it readily entered various tissues and fluids of the body. Rambo, on the basis of a single determination, concluded that it appears in the aqueous
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E. K. Marshall · Journal of the American Medical Association · 1937 · 154 citations
The Determination of Sulfanilamide
E. K. Marshall, J.T. LITCHFIELD · Science · 1938 · 85 citations
Sulfanilamide in Ophthalmia Neonatorum.
Thayer Willis · PubMed · 1938 · 18 citations