Concepedia

Chiral copper(ii) bisoxazoline covalently anchored to silica and mesoporous MCM-41 as a heterogeneous catalyst for the enantioselective Friedel–Crafts hydroxyalkylation

Avelino Corma, Hermenegildo Garcı́a, Ahmed Moussaif, María J. Sabater, Rachid Zniber, Achour Redouane

Chemical Communications · 2002 · 126 citations · 10 references

DOI

Abstract

Two solid catalysts in which a chiral copper(II) bisoxazoline has been covalently anchored on silica and MCM-41 have been prepared; the solids are enantioselective catalysts (up to 92% ee) for the Friedel-Crafts hydroxyalkylation of 1,3-dimethoxybenzene with 3,3,3-trifluoropyruvate.

References

10

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<i>C</i><sub>2</sub>-Symmetric Copper(II) Complexes as Chiral Lewis Acids. Enantioselective Catalysis of the Glyoxylate−Ene Reaction

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