Quinine and quinidine inhibition of pentobarbital metabolism

The Determination of Enzyme Dissociation Constants

Hans Lineweaver, Dean Burk · Journal of the American Chemical Society · 1934 · 12K citations

Engineering, Databases, Altmetric Attention Score +23

A simple method of estimating 50 per cent end points

Hr Muench · Medical Entomology and Zoology · 1938 · 8.4K citations

Statistics, Cent End Points, Curve Fitting

Species, strain and sex differences in metabolism of hexobarbitone, amidopyrine, antipyrine and aniline

Gwendolyn P. Quinn, Julius Axelrod, Bernard B. Brodie · Biochemical Pharmacology · 1958 · 371 citations

Biology, Comparative Endocrinology, Medicine +8

The importance of dissociaton constant and lipid-solubility in influencing the passage of drugs into the cerebrospinal fluid.

Bernard B. Brodie, H Kurz, Lewis S. Schanker · PubMed · 1960 · 255 citations

Pharmacotherapy, Experimental Pharmacology, Physical Properties +19

THE FATE OF PENTOBARBITAL IN MAN AND DOG AND A METHOD FOR ITS ESTIMATION IN BIOLOGICAL MATERIAL

Bernard B. Brodie, J.J. Burns, Lester C. Mark et al. · Journal of Pharmacology and Experimental Therapeutics · 1953 · 212 citations