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Stabilized enamine anions
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1973
Year
HalogenationEngineeringEnamine AnionsBiochemistryNatural SciencesMethylated KetonesPhenyl GroupsOrganic ChemistrySeveral KetonesChemistryStereoselective SynthesisAnion SensingEnantioselective SynthesisBiomolecular EngineeringHost-guest Chemistry
Enamines of several ketones having phenyl groups at the α or β positions have been deprotonated to give allylic anions which are reactive nucleophiles; treatment of these intermediates with methyl iodide has led to high yields of methylated ketones.