Spindle Checkpoint Protein Dynamics at Kinetochores in Living Cells

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

Valery Sudakin, Gordon K. Chan, Tim J. Yen · The Journal of Cell Biology · 2001 · 903 citations · Full text

Checkpoint Inhibition, Immunology, Cell Death +17

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

Guowei Fang, Hongtao Yu, Marc W. Kirschner · Genes & Development · 1998 · 590 citations · Full text

Budding Yeast Cdc20: A Target of the Spindle Checkpoint

Lena H. Hwang, Lucius F. Lau, Dana L. Smith et al. · Science · 1998 · 561 citations

Genome Instability, Defective Spindles, Cell Regulation +11

Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation

Bonnie J. Howell, B.F. McEwen, Julie C. Canman et al. · The Journal of Cell Biology · 2001 · 530 citations · Full text

Direct Binding of CDC20 Protein Family Members Activates the Anaphase-Promoting Complex in Mitosis and G1

Guowei Fang, Hongtao Yu, Marc W. Kirschner · Molecular Cell · 1998 · 484 citations · Full text

Signal Transduction, Molecular Physiology, Cell Division +12