JDDG Journal der Deutschen Dermatologischen Gesellschaft · 2011 · 306 citations · 93 references
MedicineDermatologyEndocrinologyDermatopathologyHuman GeneticsMedical GeneticsGenetic Hair DisordersHair DisordersAlopecia DisordersConsensusGenetic Basis Of AlopeciaHair Loss PathogenesisSystematic Literature Review
Androgenetic alopecia is the most common hair loss disorder, affecting both men and women. Initial signs of androgenetic alopecia usually develop during teenage years leading to progressive hair loss with a pattern distribution. Moreover, its frequency increases with age and affects up to 80 % Caucasian men and 42 % of women. Patients diagnosed with androgenetic alopecia may undergo significant impairment of quality of life. Despite the high prevalence and the variety of therapeutic options available, there have been no national or international evidence-based guidelines for the treatment of androgenetic alopecia in men and women so far. Therefore, the European Dermatology Forum (EDF) initiated a project to develop an evidence-based S3 guideline for the treatment of andro-genetic alopecia. Based on a systematic literature research the efficacy of the currently available therapeutic options was assessed and therapeutic recommendations were passed in a consensus conference. The purpose of the guideline is to provide dermatologists as well as general practitioners with an evidence-based tool for choosing an efficacious and safe therapy for patients with androgenetic alopecia.
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Steroid 5α-Reductase Deficiency in Man: An Inherited Form of Male Pseudohermaphroditism
Julianne Imperato‐McGinley, Luis Guerrero, Teófilo Gautier et al. · Science · 1974 · 1.3K citations
Elise A. Olsen, Frank Dunlap, Toni Funicella et al. · Journal of the American Academy of Dermatology · 2002 · 424 citations