Concepedia

Relationship between common functional polymorphisms of the p22phox gene (−930A > G and +242C > T) and nephropathy as a result of Type 2 diabetes in a Chinese population

Su Chi Lim, S. K. Goh, Yong Lai, Wee‐Wei Tee, A. Koh, Xiang-Qin Xu, Yixin Wu, E. Yap, T. Subramaniam, Chee Fang Sum

Diabetic Medicine · 2006 · 21 citations · 11 references

DOI

Abstract

In contrast with previous small studies, our data suggest that these SNPs do not confer significantly increased susceptibility to DN secondary to T2DM in Chinese subjects.

References

11

Onset of NIDDM occurs at Least 4–7 yr Before Clinical Diagnosis

Maureen I Harris, Ronald Klein, Tim Welborn et al. · Diabetes Care · 1992 · 1.3K citations

Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE

Marie‐Paule Wautier, Olivier Chappey, Stefano Corda et al. · American Journal of Physiology-Endocrinology and Metabolism · 2001 · 1K citations

, , +19

Coding single-nucleotide polymorphisms associated with complex vs. Mendelian disease: Evolutionary evidence for differences in molecular effects

Paul D. Thomas, Anish Kejariwal · Proceedings of the National Academy of Sciences · 2004 · 273 citations · Full text

, , +22

Functional Effect of the C242T Polymorphism in the NAD(P)H Oxidase p22phox Gene on Vascular Superoxide Production in Atherosclerosis

Tomasz J. Guzik, Nick E.J. West, Edward Black et al. · Circulation · 2000 · 239 citations · Full text

Polymorphism of the NADH/NADPH Oxidase <i>p22 phox</i> Gene in Patients With Coronary Artery Disease

Nobutaka Inoue, Seinosuke Kawashima, Kenji Kanazawa et al. · Circulation · 1998 · 238 citations · Full text