Oral administration of homocysteine leads to increased plasma triglycerides and homocysteic acid — additional mechanisms in homocysteine induced endothelial damage?

Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease

Robert Clarke, Leslie Daly, Killian Robinson et al. · New England Journal of Medicine · 1991 · 2.2K citations · Full text

Life Sciences, Biochemistry, Cardiology +15

Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen.

Jonathan S. Stamler, John A. Osborne, O Jaraki et al. · Journal of Clinical Investigation · 1993 · 867 citations · Full text

Life Sciences, Biochemistry, Physiology +13

Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine.

Gordon Starkebaum, John M. Harlan · Journal of Clinical Investigation · 1986 · 823 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease.

M.R. Malinow, Seok Seon Kang, Lloyd M. Taylor et al. · Circulation · 1989 · 509 citations · Full text

Medicine, Biochemistry, Cardiology +10

Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults. The Atherosclerosis Risk in Communities Study.

M.R. Malinow, F. Javier Nieto, Moysés Szklo et al. · Circulation · 1993 · 454 citations

Medicine, Cardiology, Internal Medicine +16