Concepedia

Overexpression of Eotaxin and the CCR3 Receptor in Human Atherosclerosis

Kathleen J. Haley, Craig M. Lilly, Jeong-Hee Yang, Yajun Feng, Scott P. Kennedy, Thomas G. Turi, John F. Thompson, Galina H. Sukhova, Peter Libby, Richard Lee

Circulation · 2000 · 250 citations · 21 references

DOI

Abstract

Eotaxin and its receptor, CCR3, are overexpressed in human atherosclerosis, suggesting that eotaxin participates in vascular inflammation. These data demonstrate how genomic differential expression technology can identify novel genes that may participate in the stability of atherosclerotic lesions.

References

21

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.2K citations

, , +7

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Piotr Chomczyński, Nicoletta Sacchi · Analytical Biochemistry · 1987 · 46.8K citations

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Expression monitoring by hybridization to high-density oligonucleotide arrays

David J. Lockhart, Helin Dong, Michael C. Byrne et al. · Nature Biotechnology · 1996 · 2.8K citations

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The Transcriptional Program in the Response of Human Fibroblasts to Serum

Vishwanath R. Iyer, Michael B. Eisen, Douglas T. Ross et al. · Science · 1999 · 2K citations

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Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis

Landin Boring, Jennifa Gosling, Michael D. Cleary et al. · Nature · 1998 · 2K citations

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