Concepedia

Mdm2 overexpression and p73 loss exacerbate genomic instability and dampen apoptosis, resulting in B-cell lymphoma

Maurisa F. Riley, M. James You, Asha S. Multani, Guillermina Lozano

Oncogene · 2015 · 18 citations · 32 references

DOI

Concepts

References

32

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

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Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo.

Toshiyuki Miyashita, Stanisław Krajewski, Maryla Krajewska et al. · PubMed · 1994 · 2.2K citations

, , +13

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

Roberto Montes de Oca Luna, Daniel S. Wagner, Guillermina Lozano · Nature · 1995 · 1.4K citations

, , +12

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

Stephen N. Jones, Amy E. Roe, Lawrence A. Donehower et al. · Nature · 1995 · 1.3K citations

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p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

Annie Yang, Nancy Walker, Roderick T. Bronson et al. · Nature · 2000 · 987 citations

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