Journal of the American Medical Association · 1929 · 47 citations · 6 references
MedicineEndocrinologyGynecologyReproductive EndocrinologyReproductive MedicineReproductive PhysiologyGynecologic EndocrinologyHormonal EvaluationOvarian DisordersOvarian FunctionOvarian PhysiologyPregnancy EndocrinologyAnterior Pituitary Hormone SecretionFemale Reproductive EndocrinologyGonadal Hormone TestingHormonal DiagnosticsHypothalamic-pituitary-ovarian Axis DysfunctionOvarian HypofunctionPituitary Hormone AssaysRadiation Effects On The Endocrine System
The recent development of methods to determine the presence of the hormone (or hormones) of the anterior lobe of the hypophysis in the blood or urine of patients has opened a new field of study which may prove of much clinical assistance in the diagnosis and treatment of certain endocrine disturbances. In a previous communication<sup>1</sup>the results of tests for the presence of anterior pituitary hormone in the blood of pregnant women were given, and attention was directed to a number of positive changes following an operative or radiation castration. The present report deals with the study of a small series of patients with (1) a total extirpation of the ovaries, (2) a radiation castration, (3) a functional amenorrhea, or (4) irregular menstruation. The method used in this investigation is based on the "pregnancy test" of Zondek and Aschheim,<sup>2</sup>and consists in a microscopic study of the changes
6
CLINICAL DATA OBTAINED WITH THE FEMALE SEX HORMONE BLOOD TEST
Robert T. Frank · JAMA · 1928 · 31 citations
Medicine, Endocrinology, Gynecology +11