A toxicological and pharmacological study of ibuprofen guaiacol ester (AF 2259) in the rat

A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS

J.T. LITCHFIELD, Frank Wilcoxon · Journal of Pharmacology and Experimental Therapeutics · 1949 · 7.3K citations

Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs

C. A. Winter, Edwin A. Risley, George W. Nuss · Experimental Biology and Medicine · 1962 · 5.6K citations

Inflammation, Rheumatology, Anti-inflammatory +13

The role of direct tissue contact in the production of gastrointestinal ulcers by anti-inflammatory drugs in rats

V. Cioli, S Putzolu, Vilma Rossi et al. · Toxicology and Applied Pharmacology · 1979 · 219 citations

Inflammation, Anti-inflammatory, Gastrointestinal Ulcers +10

Drug screening and evaluation of new compounds in animals

S. T. Irwin · 1964 · 57 citations

Preclinical Drug Evaluation, Pharmacological Study, Medicine +6

Evaluation of the potential of gastric ulceration after administration of certain drugs

V. Cioli, Bruno Silvestrini, F Dordoni · Experimental and Molecular Pathology · 1967 · 54 citations

Gastrointestinal Pharmacology, Medicine, Gastroenterology +6