Intratumoural budding (ITB) in preoperative biopsies predicts the presence of lymph node and distant metastases in colon and rectal cancer patients

Inti Zlobec, Marion Hädrich, Heather Dawson, Viktor H. Koelzer, Markus Borner, Makhmudbek Mallaev, Beat Schnüriger, Daniel Inderbitzin, Alessandro Lugli

British Journal of Cancer · 2013 · 92 citations · 24 references

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Abstract

Tumour budding can be assessed in the preoperative biopsy of CRC patients. It is practical, reproducible and predictive of LN and distant metastasis. Intratumoural budding qualifies for further investigation in the prospective setting.

References

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