Organic Letters · 2010 · 177 citations · 45 references
Natural SciencesChemical EngineeringChemistryCatalysisMagnetic MaterialsOrganometallic ChemistryCatalyst DesignCatalyst PreparationCatalyst SynthesisCatalytic MaterialsNanocatalysisSupported CatalystsCopper CatalysisEnantioselective CatalysisEnantioselective SynthesisEnantioselectivityMagnetic Nanoparticle SupportsReactivitySupported Metal CatalystsSupported Nanocatalysts
An Fe(3)O(4) nanoparticle-supported copper(I) pybox catalyst, which exhibits excellent reactivity and yields products with good enantioselectivity, was developed. As a proof of concept, six optically active propargyl amines were obtained in excellent yields. The catalyst can be magnetically removed and recycled easily six times without a decrease in activity or enantioselectivity.
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