Nitriles in heterocyclic synthesis: A novel route for the synthesis of naphthodipyrans, pyridines. 2H- and 4H-Pyrans

Abstract

Naphtho[2,1- b :5,6- b ']dipyrans and naphtho[1,2- b :6,5- b ']dipyrans were synthesized by the reaction of cinnamonitriles with 2,3-, 1,5-, 1,6-naphthalenediols, respectively. Polysubstituted pyridines, 2 H -pyrans and 4 H -pyrans were also synthesized from cinnamonitriles, 2-hydroxyacetophenone and 3-acetyl-4-hydroxy-1-methylcarbostyril, respectively.