Antimicrobial resistance issues of the future

Correlation of Antimicrobial Pharmacokinetic Parameters with Therapeutic Efficacy in an Animal Model

Bennett Vogelman, J. E. Leggett, John Turnidge et al. · The Journal of Infectious Diseases · 1988 · 721 citations

Pharmacy, Infectious Diseases, Pharmacokinetics +13

Comparative Antibiotic Dose-Effect Relations at Several Dosing Intervals in Murine Pneumonitis and Thigh-Infection Models

J. E. Leggett, B. Fantin, Steven C. Ebert et al. · The Journal of Infectious Diseases · 1989 · 353 citations

Medicine, Pharmacokinetics, Pharmacology +17

Persistent Effect of Antibiotics on Staphylococcus aureus after Exposure for Limited Periods of Time

P. J. McDonald, William A. Craig, C. M. Kunin · The Journal of Infectious Diseases · 1977 · 195 citations

Life Sciences, Infectious Diseases, Microbiology +13

National collaborative study of the prevalence of antimicrobial resistance among clinical isolates of Haemophilus influenzae

Gary V. Doern, J. H. Jorgensen, C Thornsberry et al. · Antimicrobial Agents and Chemotherapy · 1988 · 173 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +11

Comparative dose-effect relations at several dosing intervals for beta-lactam, aminoglycoside and quinolone antibiotics against gram-negative bacilli in murine thigh-infection and pneumonitis models.

J. E. Leggett, Steven C. Ebert, B. Fantin et al. · PubMed · 1990 · 133 citations

Medicine, Pharmacokinetics, Pharmacology +15