The Calcimimetic NPS R-568 Decreases Plasma PTH in Rats with Mild and Severe Renal or Dietary Secondary Hyperparathyroidism

Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid

Edward M. Brown, Gerardo Gamba, Daniela Riccardi et al. · Nature · 1993 · 2.6K citations

Life Sciences, Biochemistry, Physiology +14

Calcimimetics with potent and selective activity on the parathyroid calcium receptor

Edward F. Nemeth, Michael E. Steffey, Lance G. Hammerland et al. · Proceedings of the National Academy of Sciences · 1998 · 612 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro.

Eduardo Slatopolsky, Jane Finch, Masashi Denda et al. · Journal of Clinical Investigation · 1996 · 512 citations · Full text

Medicine, Endocrinology, Nephrology +17

Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism

Jean Gogusev, Patricia Duchambon, B Hory et al. · Kidney International · 1997 · 494 citations

Medicine, Endocrinology, Pathology +16

Direct effect of phosphorus on PTH secretion from whole rat parathyroid glands in vitro

Yolanda Almadén, Antonio Canalejo, Alexis Hernández et al. · Journal of Bone and Mineral Research · 1996 · 333 citations

Medicine, Endocrinology, Physiology +17