Effects of a bisphosphonate (1-hydroxy ethylidene-1,1 bisphosphonic acid) on osteoclast number during prolonged bed rest in healthy humans

Quantitative histological data on disuse osteoporosis

P Minaire, Pierre J. Meunier, C Edouard et al. · Calcified Tissue International · 1974 · 439 citations

Medicine, Orthopedic Surgery, Pathology +11

Two modes of action of bisphosphonates on osteoclastic resorption of mineralized matrix.

Boonekamp Pm, van Wijk-van Lennep, Thesing Cw et al. · PubMed · 1986 · 349 citations

Medicine, Orthopaedic Surgery, Biomaterials +13

Quantitative histology of metabolic bone disease

Ph. Bordier, S. Tun Chot · Clinics in Endocrinology and Metabolism · 1972 · 168 citations

Medicine, Orthopedic Surgery, Pathology +14

Kinetic studies of bone and mineral metabolism during treatment with (3-amino-1-hydroxypropylidene)-1,1-bisphosphonate (APD) in rats

Pieter H. Reitsma, O. L. M. Bijvoet, Harmke Verlinden-Ooms et al. · Calcified Tissue International · 1980 · 161 citations

Medicine, Pharmacokinetics, Pharmacology +14

Bisphosphonates--history and experimental basis.

H. Fleisch · PubMed · 1987 · 154 citations

Medicine, Medicinal Chemistry, Bone Metabolism +6