Concepedia

Chfr is required for tumor suppression and Aurora A regulation

Xiaochun Yu, Katherine Minter‐Dykhouse, Liviu Malureanu, Wei-meng Zhao, Dongwei Zhang, Carolin J Merkle, Irene M. Ward, Hideyuki Saya, Guowei Fang, Jan van Deursen,

Nature Genetics · 2005 · 196 citations · 26 references

DOI

Concepts

References

26

Mutations of mitotic checkpoint genes in human cancers

Daniel P. Cahill, Christoph Lengauer, Jian Yu et al. · Nature · 1998 · 1.5K citations

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Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

Hongyi Zhou, Jian Kuang, Ling Zhong et al. · Nature Genetics · 1998 · 1.3K citations

, , +12

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

James R. Bischoff · The EMBO Journal · 1998 · 1.2K citations · Full text

, , +14

Aurora‐A overexpression reveals tetraploidization as a major route to centrosome amplification in p53−/− cells

Patrick Meraldi · The EMBO Journal · 2002 · 654 citations · Full text

, , +15

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

Shubha Anand, Sue Penrhyn-Lowe, Ashok R. Venkitaraman · Cancer Cell · 2003 · 641 citations · Full text

, , +13