An in situ evidence for autocrine function of NO in the vasculature

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

Life Sciences, Cell Biology, Physiology +15

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Richard Palmer, Anthony G. Ferrige, Salvador Moncada · Nature · 1987 · 10.8K citations

Veterinary Medicine, Cell Biology, Physiology +10

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

Richard Palmer, Daryl D. Rees, David Ashton et al. · Biochemical and Biophysical Research Communications · 1988 · 1.4K citations

Life Sciences, Biochemistry, Physiology +9

Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.

Louis J. Ignarro, R E Byrns, Georgette M. Buga et al. · Circulation Research · 1987 · 1.2K citations

Medicine, Biochemistry, Pharmacology +8

Nitric oxide in skeletal muscle

Lester Kobzik, Michael B. Reid, David S. Bredt et al. · Nature · 1994 · 961 citations

Life Sciences, Biochemistry, Physiology +11