Identification of two distinct regulatory regions adjacent to the human β-interferon gene

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

John M. Chirgwin, Alan Przybyla, Raymond J. MacDonald et al. · Biochemistry · 1979 · 22.2K citations

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[57] Sequencing end-labeled DNA with base-specific chemical cleavages

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Selective extraction of polyoma DNA from infected mouse cell cultures

Bernhard Hirt · Journal of Molecular Biology · 1967 · 5.3K citations

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Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

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Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

Peter J. Southern, Paul Berg · PubMed · 1982 · 2.8K citations

Life Sciences, Genetics, Molecular Biology +17