Effect of Etomidate on the Electroencephalogram of Patients with Epilepsy

Zeyd Ebrahim, Glenn E. DeBoer, Hans O. Lüders, Joseph F. Hahn, Ronald P. Lesser

Anesthesia & Analgesia · 1986 · 105 citations · 0 references

Concepts

Abstract

Etomidate was given intravenously to 12 epileptic patients undergoing craniotomy for surgical removal of their seizure focus. Electroencephalograms were recorded by means of subdural electrodes. Nine of the 12 patients showed an increase in epileptiform activity. In six of the nine patients, the activity was marked.