Peripherally Substituted Cobaloximes; X‐ray Crystal Structure Analysis of σ‐Hexylbis[1,8‐di(<i>N</i>‐morpholino)octane‐4,5‐dioximato]pyridinecobalt(<scp>III</scp>)

Abstract

Unexpected eliminations defeated attempts to synthesize alkylcobaloximes substituted with α- and β-heteroatoms. However, synthesis of the γ-substituted alkylcobaloxime 1, a functionalized coenzyme B12 model, was successful in only a few steps. The key step was an acyloin condensation for the preparation of the dioxime ligand.