Concepedia

Acquisition of the ts phenotype by a chemically mutagenized cold-passaged human respiratory syncytial virus vaccine candidate results from the acquisition of a single mutation in the polymerase (L) gene

James E. Crowe, Cai-Yen Firestone, Stephen S. Whitehead, Peter L. Collins, Brian R. Murphy

Virus Genes · 1996 · 35 citations · 22 references

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Concepts

References

22

Identification of four conserved motifs among the RNA‐dependent polymerase encoding elements.

Olivier Poch, Isabelle Sauvaget, Marc Delarue et al. · The EMBO Journal · 1989 · 1.2K citations · Full text

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Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in gene expression and provides a capability for vaccine development.

Peter L. Collins, M G Hill, Ena Camargo et al. · Proceedings of the National Academy of Sciences · 1995 · 447 citations

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Transcription elongation factor of respiratory syncytial virus, a nonsegmented negative-strand RNA virus.

Peter L. Collins, M G Hill, Juan Cristina et al. · Proceedings of the National Academy of Sciences · 1996 · 298 citations

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Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines

M H Snyder, Robert F. Betts, Dan C. DeBorde et al. · Journal of Virology · 1988 · 159 citations · Full text

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Rescue of synthetic analogs of respiratory syncytial virus genomic RNA and effect of truncations and mutations on the expression of a foreign reporter gene.

Patrick L. Collins, Michael A. Mink, David S. Stec · Proceedings of the National Academy of Sciences · 1991 · 144 citations

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