Journal of the American Medical Association · 1959 · 12 citations · 7 references
MedicineHematologySurgeryHemostasisPulmonologyTransfusion MedicineHemolytic DisordersHemostatic DisordersThoracic SurgeryBlood Bank ManagementHemorrhagic ManifestationsImmune Globulin TherapySpontaneous PneumothoraxStab Wound ManagementTransfusion-related Hemolysis
Despite the diversity of hemorrhagic complications encountered in patients with hemophilia, bleeding within the chest is uncommon. In 1943, review of the early literature by Freedman and associates<sup>1</sup>revealed only two cases of hemorrhagic disease complicated by hemothorax; neither patient was a hemophiliac. These authors reported a 22-year-old man with a familial history and laboratory studies characteristic of hemophilia, whose spontaneous hemothorax was treated successfully by repeated thoracenteses and "numerous small transfusions." A similar case had been reported by Pendergrass and Neuhauser<sup>2</sup>the year before. In 1957, Kay and Kupfer<sup>3</sup>reported a spontaneous hemothorax in a proved hemophiliac successfully treated by thoracenteses and infusions of antihemophilic globulin. In 1953, in the Polish literature, Juszczynski<sup>4</sup>reported a stab wound of the chest successfully treated by thoracotomy in a presumed hemophiliac. The response of this patient to stored bank blood suggests that this was actually a case of
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On the Quantitative Estimation of Prothrombin
Armand J. Quick · American Journal of Clinical Pathology · 1945 · 141 citations
Medicine, Biochemistry, Pathology +10
Benjamin Alexander, Robert H. Goldstein, Greta Landwehr et al. · Journal of Clinical Investigation · 1951 · 31 citations · Full text