Peripheral Blood <scp>NK</scp> Cell Cytotoxicities are Negatively Correlated with <scp>CD</scp>8⁺ T Cells in Fertile Women but not in Women with a History of Recurrent Pregnancy Loss

Abstract

NK cell-mediated immunopathology plays a role in RPL. Women with RPL have a disrupted immune regulation between cytotoxic T and NK cells. Failure of immune modulation by CD8(+) T cells may exert NK cell activation and reproductive failures in women with RPL.