The Cancer Journal · 2002 · 82 citations · 41 references
The use of a rectal balloon during intensity-modulated radiotherapy significantly reduces prostate motion. Prostate immobilization thus allows a safer and smaller planning target volume margin. It has also helped spare the anterior rectal wall (by its dosimetric effects) and reduced the rectal volume that received high-dose radiation (by rectal wall distension). All these factors may have further contributed to the decreased rectal toxicity achieved by intensity-modulated radiotherapy, despite dose escalation and higher-than-conventional fraction size.
41
Michael J. Zeléfsky, StevenA Leibel, PaulB Gaudin et al. · International Journal of Radiation Oncology*Biology*Physics · 1998 · 926 citations
Adaptive Radiotherapy, Radiation Medicine, Radiation Therapy +9
David J. Brenner, Alvaro A. Martinez, Gregory K. Edmundson et al. · International Journal of Radiation Oncology*Biology*Physics · 2002 · 653 citations