Estrogens promote proliferation of the seminoma-like TCam-2 cell line through a GPER-dependent ERα36 induction

Identity of an Estrogen Membrane Receptor Coupled to a G Protein in Human Breast Cancer Cells

Peter Thomas, Yefei Pang, Edward J. Filardo et al. · Endocrinology · 2004 · 1.4K citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth Factor Receptor through Release of HB-EGF

Edward J. Filardo, Jeffrey A. Quinn, Kirby I. Bland et al. · Molecular Endocrinology · 2000 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

POSSIBLE CARCINOMA-IN-SITU OF THE TESTIS

NielsE. Skakkebæk · The Lancet · 1972 · 746 citations

Veterinary Medicine, Oncology, Pathology +13

Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: A potential novel mechanism of endocrine disruption

Peter Thomas, Jing Dong · The Journal of Steroid Biochemistry and Molecular Biology · 2006 · 594 citations

Life Sciences, Endocrinology, Molecular Biology +15

In vivo effects of a GPR30 antagonist

Megan K. Dennis, Ritwik Burai, Chinnasamy Ramesh et al. · Nature Chemical Biology · 2009 · 521 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +6