Rh(<scp>i</scp>)-catalyzed decarbonylative direct C2-olefination of indoles with vinyl carboxylic acids

Abstract

A general and efficient Rh(I)-catalyzed decarbonylative direct C2-olefination of indoles with vinyl carboxylic acids has been developed. The reaction exhibits excellent functional group tolerance, regioselectivity and stereoselectivity, giving a broad range of C2-alkenylated indoles in good to excellent yields.