The Drosophila tankyrase regulates Wg signaling depending on the concentration of Daxin

β-catenin is a target for the ubiquitin–proteasome pathway

Hermann Aberle, Andreas Bauer, Jörg Stappert et al. · The EMBO Journal · 1997 · 2.5K citations · Full text

Protein Function, Molecular Regulation, Medicine +6

Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism

Chunming Liu, Yiming Li, Mikhail A. Semenov et al. · Cell · 2002 · 2.1K citations · Full text

Signal Transduction, Signaling Pathway, Dual-kinase Mechanism +6

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

Shih-Min A. Huang, Yuji Mishina, Shanming Liu et al. · Nature · 2009 · 2.1K citations

Tankyrase Inhibition, Signal Transduction, Signaling Pathway +7

Induction of Ectopic Eyes by Targeted Expression of the <i>eyeless</i> Gene in <i>Drosophila</i>

Georg Halder, Patrick Callaerts, Walter J. Gehring · Science · 1995 · 1.6K citations

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta -catenin and promotes GSK-3beta -dependent phosphorylation of beta -catenin

Satoshi Ikeda · The EMBO Journal · 1998 · 1.2K citations · Full text

Beta -Catenin, Signal Transduction, Negative Regulator +10