Reduction of dopamine release and synthesis by repeated amphetamine treatment: Role in behavioral sensitization

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

G. Di Chiara, Assunta Impérato · Proceedings of the National Academy of Sciences · 1988 · 4.7K citations · Full text

Medicine, Neuroscience, Pharmacology +17

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

Bruno Giros, Mohamed Jaber, Sara R. Jones et al. · Nature · 1996 · 2.5K citations

Life Sciences, Neuroscience, Pharmacology +12

Tolerance and sensitization to the behavioral effects of drugs

Jane Stewart, Aldo Badiani · Behavioural Pharmacology · 1993 · 595 citations

Medicine, Behavioral Sciences, Psychology +14

Amphetamine Psychosis: A "Model" Schizophrenia Mediated by Catecholamines

Solomon H. Snyder · American Journal of Psychiatry · 1973 · 588 citations

Medicine, Pharmacology, Psychiatry +17

A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function

Rose Z. Terwilliger, Dana Beitner‐Johnson, Kevin A. Sevarino et al. · Brain Research · 1991 · 540 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17