Artificial Organs · 1999 · 14 citations · 10 references
MedicineCardiologySurgeryCardiothoracic SurgeryComputational Fluid DynamicsSurgical InstrumentationCardiovascular System ModelingExtracorporeal CirculationHemodynamicsHemodynamics ModelingBlood FlowLeft Ventricular Assist DevicesMechanical DamageNumerical Flow SimulationNumerical SimulationPulsation PumpsPump ConfigurationsPump Flow Dynamics
The pulsating catheter (PUCA) pump, a left ventricular assist device, consists of a hydraulically or pneumatically driven membrane pump, extracorporeally placed and mounted to a valved catheter. The catheter is introduced into an easily accessible artery and positioned with its distal tip in the left ventricle. Blood is aspirated from the left ventricle during systole and ejected into the ascending aorta during diastole. A numerical model of the PUCA pump has been developed to determine the internal diameter of the PUCA pump catheter that allows a certain blood flow. The model considers a limitation of mechanical blood damage and determines the accompanying pressure and flow profile for driving the pump. For a flow of 5 L/min, a catheter with an internal diameter of at least 6. 95 mm is required. For 3 L/min, the minimal diameter is 5.50 mm. The latter catheter can be introduced in the axillary artery, the former via the aorta during an open thorax surgical procedure. To validate the numerical model, 2 different PUCA pump configurations were tested in vitro. Results showed a good resemblance between model and in vitro behavior of the PUCA pump.
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SOME MECHANICAL EFFECTS THAT INFLUENCE HEMOLYSIS
Perry L. Blackshear, Frank D. Dorman, Joseph H. Steinbach · ASAIO Journal · 1965 · 184 citations
Engineering, Bioengineering, Surgery +15
Cavitation Potential of Mechanical Heart Valve Prostheses
T. Graf, H. Fischer, H. Reul et al. · The International Journal of Artificial Organs · 1991 · 94 citations
Medicine, Cardiology, Surgery +16
Kouji Fukae, Ryuji Tominaga, Shigehiko Tokunaga et al. · Journal of Thoracic and Cardiovascular Surgery · 1996 · 80 citations · Full text
Veterinary Medicine, Veterinary Internal Medicine, Veterinary Physiology +12