Structure–activity relationships amongst 4-position quinoline methanol antimalarials that inhibit the growth of drug sensitive and resistant strains of Plasmodium falciparum

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

Carlos Cordon‐Cardo, James P. O’Brien, D Casals et al. · Proceedings of the National Academy of Sciences · 1989 · 1.7K citations · Full text

Medicine, Oncology, Pharmacology +16

Pd/P(<i>t</i>-Bu)₃:  A Mild and General Catalyst for Stille Reactions of Aryl Chlorides and Aryl Bromides

Adam F. Littke, Lothar Schwarz, Gregory C. Fu · Journal of the American Chemical Society · 2002 · 447 citations

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Neuropsychiatric Side Effects after the use of Mefloquine

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Medicine, Pharmacology, Psychiatry +14

Mefloquine (WR 142,490) in the Treatment of Human Malaria

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Medicine, Pharmacology, Pharmacotherapy +17

The intramolecular Stille reaction

Matthew A. J. Duncton, Gerald Pattenden · Journal of the Chemical Society Perkin Transactions 1 · 1999 · 146 citations

Natural Sciences, Chemistry, Organic Chemistry +2