Science · 1966 · 316 citations · 9 references
Rat BoneAnorphous Calcium PhosphateOsteoporosisOrthopaedic SurgeryBone DiseaseBiomechanicsOsteoarthritisAge DependencyCrystalline Mineral FractionsHealth SciencesMechanobiologyAmorphous Calcium PhosphateBone HealthCrystalline Calcium PhosphateSkeletal BiologyBone DensityBone MetabolismOsteocalcinBone ImagingHydroxyapatitePhysiologyMedicine
Quantitative infrared spectrophotometric analysis of whole femurs from male rats demonstrates that anorphous calcium phosphate is a major component of bone mineral. The amount of amorphous calcium phosphate in whole bone decreases while the crystalline bone apatite increases during early stages of bone formation. Mature rat bone contains constant levels of both amorphous and crystalline calcium phosphate.
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