Chemistry Letters · 2010 · 26 citations · 46 references
Natural SciencesChemistryAnalytical ChemistryBiosensorsOrganic ChemistryChemical Probe DiscoveryChemical SensorsColor AnalysisMolecular Probe DevelopmentMolecular SensorsAqueous Reaction MediaColorimetric Anion SensingColorimetric BiosensorsColorimetric ScreeningColorimetric TestsNucleophilic ReactivitySelectivitySensing In Aqueous Media
Abstract A new cyanide anion colorimetric probe was developed using a chromene derivative, 7-nitro-2,3-dihydro-1H-cyclopenta[b]chromen-1-one (1). The molecule exhibited much higher selectivity and sensitivity for detecting cyanide anion compared with other anions, F−, Cl−, Br−, I−, SCN−, AcO−, NO3−, ClO4−, SO42−, PO43−, SO32−, CO32−, and C2O42−, in aqueous media through a visual color change from colorless to yellow. The mechanism was proposed to be a novel chromene ring-opening, resulting from a nucleophilic attack on the probe 1 by CN− anion.
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