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Structural modification of 3-arylisoquinolines to isoindolo[2,1-b]isoquinolinones for the development of novel topoisomerase 1 inhibitors with molecular docking study

Combinatorial ChemistryMedicinal ChemistryMolecular Docking StudyEngineeringBiochemistryNatural SciencesRational Drug DesignOrganic ChemistryStructural ModificationPharmacologyNovel Topoisomerase 1Drug Discovery