Activation of FGF Receptors is a new Mechanism by which Strontium Ranelate Induces Osteoblastic Cell Growth

Abstract

data presented in this study suggest that activation of FGFRs is a new potential mechanism by which strontium can stimulate osteoblastic cell growth. Activation of FGFR-dependent cell growth is also observed in response to other cations suggesting that activation of FGF receptors is a new cation sensing mechanism in osteoblasts.