Structures of bacillomycin D and bacillomycin L peptidolipid antibiotics from Bacillus subtilis.

Abstract

The complete structures of bacillomycin D and bacillomycin L were revised by FAB mass spectrometry and by Edman degradation of the derivatives resulting from the N-bromosuccinimide reaction. The homologous components of both series of antibiotics were separated by HPLC and the beta-amino acids were identified by capillary gas chromatography.