Myocardial Apelin Production is Reduced in Humans With Left Ventricular Systolic Dysfunction

Isolation and Characterization of a Novel Endogenous Peptide Ligand for the Human APJ Receptor

Kazuhiko Tatemoto, Masaki Hosoya, Yugo Habata et al. · Biochemical and Biophysical Research Communications · 1998 · 1.7K citations

Signal Transduction, G Protein-coupled Receptor, Medicine +8

Localization and mechanism of secretion of B-type natriuretic peptide in comparison with those of A-type natriuretic peptide in normal subjects and patients with heart failure.

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A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

Brian F. O’Dowd, Michael Heiber, Audrey Chan et al. · Gene · 1993 · 832 citations

Systems Biology, Genetics, Human Polymorphism +11

Characterization of Apelin, the Ligand for the APJ Receptor

Dennis K. Lee, Regina Cheng, Tuan Nguyen et al. · Journal of Neurochemistry · 2000 · 674 citations

Rat Preproapelin, Rat Apelin, Gastrointestinal Peptide Hormone +17

The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

Kazuhiko Tatemoto, Kiyoshige Takayama, Min‐Xu Zou et al. · Regulatory Peptides · 2001 · 639 citations

Hypertension, Neuropeptides, Molecular Physiology +8