A novel cycloalkylation of 1,6- and 1,7-enynes with stabilized pronucleophiles

Abstract

Formation of five and six membered rings simultaneously with addition of a functionalized side chain for further elaboration occurred upon exposing a 1:1 mixture of an enyne and a pronucleophile to a palladium catalyst derived from Pd(OAc)2 and a bidentate ligand.