Concepedia

The Effect of Recombinant Factor VIIa on Coagulopathic Pigs with Grade V Liver Injuries

Martin A. Schreiber, John B. Holcomb, Ulla Hedner, Susan I. Brundage, Joseph M. Macaitis, Keith Hoots

The Journal of Trauma: Injury, Infection, and Critical Care · 2002 · 125 citations · 19 references

DOI

Abstract

rFVIIa reduces blood loss in hypothermic, dilutionally coagulopathic pigs with grade V injuries when used as an adjunct to packing. Increasing the dose does not enhance the hemostatic effect.

References

19

Organ Injury Scaling

Ernest E. Moore, Thomas H. Cogbill, Gregory J. Jurkovich et al. · 1995 · 1.1K citations

, , +18

Recombinant Activated Factor VII for Adjunctive Hemorrhage Control in Trauma

U. Martinowitz, Gili Kenet, Eran Segal et al. · The Journal of Trauma: Injury, Infection, and Critical Care · 2001 · 448 citations

Prospective, Randomised Trial of Two Doses of rFVIIa (NovoSeven) in Haemophilia Patients with Inhibitors Undergoing Surgery

Thrombosis and Haemostasis · 1998 · 372 citations

, , +14

Recombinant factor VIIa corrects prothrombin time in cirrhotic patients: A preliminary study

DE Bernstein, L. Jeffers, Elisabeth Erhardtsen et al. · Gastroenterology · 1997 · 254 citations

The Effects of Hydroxyethyl Starches of Varying Molecular Weights on Platelet Function

Alexander Franz, P. Bräunlich, Thomas Gamsjäger et al. · Anesthesia & Analgesia · 2001 · 229 citations