Antibiofilm and quorum sensing inhibitory activity of<i>Achyranthes aspera</i>on cariogenic<i>Streptococcus mutans</i>: An<i>in vitro</i>and<i>in silico</i>study

Abstract

Anticaries bioactive compounds of A. aspera with higher QS response regulator binding energy, low toxicity and optimal pharmacokinetic properties were revealed. These compounds with possible QQ ability hold the potential for use as anticaries drug leads and antibiofilm preventative medicine.