Mitogen activated protein kinase inhibition by PD98059 blocks nerve growth factor stimulated axonal outgrowth from adult mouse dorsal root ganglia in vitro

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

Dario R. Alessi, Ana Cuenda, Philip Cohen et al. · Journal of Biological Chemistry · 1995 · 3.4K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +13

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

David T. Dudley, Long Pang, Stuart J. Decker et al. · Proceedings of the National Academy of Sciences · 1995 · 2.7K citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Phosphorylation of c-jun mediated by MAP kinases

Bernd Pulverer, John Kyriakis, Joseph Avruch et al. · Nature · 1991 · 1.5K citations

Life Sciences, Biochemistry, Molecular Biology +8

Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve

Dan Lindholm, Rolf Heumann, Michaël Meyer et al. · Nature · 1987 · 998 citations

Life Sciences, Neurobiology, Neuroscience +11

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

Long Pang, Takeshi Sawada, Stuart J. Decker et al. · Journal of Biological Chemistry · 1995 · 905 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15