Safety and Pharmacokinetics of Escalating Doses of Human Recombinant Nerve Growth Factor Eye Drops in a Double-Masked, Randomized Clinical Trial

Mauro P. Ferrari, Flavio Mantelli, Marta Sacchetti, Maria Irene Antonangeli, Franca Cattani, Gaetano D’Anniballe, Francesco Sinigaglia, Pier Adelchi Ruffini, Alessandro Lambìase

BioDrugs · 2013 · 73 citations · 18 references

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Abstract

rhNGF eye drops were well tolerated, with no detectable clinical evidence of systemic AEs. These results pave the way for the development of clinical trials on rhNGF in ophthalmology.

References

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