Integrative Cancer Therapies · 2006 · 76 citations · 21 references
MedicineEndocrinologyOncologyEndocrine OncologyEndocrine PharmacotherapyNeuro-oncologyHormonal TherapyHormone-secreting TumorsPituitary SurgeryPituitary TumorsCancer-related SymptomsLocomotionPituitary CarcinomaPituitary DysfunctionPituitary Macroadenoma ImagingPituitary PathologyPituitary Tumor PathologyPituitary Tumor-related Visual Loss
INTRODUCTION: This report describes the case of a male patient with pituitary macroadenoma treated with the artemisinin analog artemether. PATIENT AND METHODS: A 75 year-old male patient presented with vision, hearing, and locomotion-related problems. Artemether was administered orally to the patient over a period of 12 months. RESULTS: Although the tumor remained consistent in size, CT scan shows a reduction in its density, and clinically, the related symptoms and signs resolved significantly as therapy progressed. DISCUSSION: Overall, the artemether treatment was beneficial in improving the patient's quality of life. Artemether and other artemisinin analogs offer promise for cancer therapy.
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The anti-malarial artesunate is also active against cancer
Thomas Efferth, Heather M. Dunstan, Axel Sauerbrey et al. · International Journal of Oncology · 2001 · 570 citations
Quality of Life in Patients with a Pituitary Adenoma
Michelle D. Johnson, C. J. Woodburn, Mary Lee Vance · Pituitary · 2003 · 229 citations
Medicine, Endocrinology, Surgery +11