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Anti-Thrombosis Effect of Paeoniflorin: Evaluated in a Photochemical Reaction Thrombosis Model<i>in vivo</i>
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2001
Year
Arachidonic Acid MetabolismBiomedical EngineeringOxidative StressThrombosisHematologyPhototoxicityClinical ChemistryPhotosensitizersAtherosclerosisHealth SciencesBiochemistryPhotochemistryFibrinolysisVascular BiologyPharmacologyThrombopoiesisBlood PlateletFree RadicalThromobosis TimeMedicineAnti-thrombosis Effect
In a photochemical reaction microvessel thrombosis model, the anti-thrombotic effect of PT was evaluated and the results showed that PF could significantly prolong thromobosis time. The anti-thrombotic effect of PF may relate to the inhibition of arachidonic acid metabolism, the increase of t-PA activity, and the protective effect against free radical.