Concepedia

Berberine Suppresses TPA-Induced Fibronectin Expression through the Inhibition of VEGF Secretion in Breast Cancer Cells

Sangmin Kim, Soo Jin Oh, Jeongmin Lee, Jeonghun Han, Myeongjin Jeon, Taewoo Jung, Se Kyung Lee, Soo Youn Bae, Jiyoung Kim, Won Ho Gil,

Cellular Physiology and Biochemistry · 2013 · 43 citations · 25 references

DOIFull text

Open access

Abstract

Taken together, we suggest that BBR may suppress TPA-induced VEGF and FN as well as VEGF-induced FN through the inhibition of the PI-3K/AKT pathway in breast cancer cells. Therefore, we suggest that BBR may be used as a candidate drug for the inhibition of angiogenesis of human breast cancer.

References

25

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