LASER THERAPY · 1990 · 54 citations · 15 references
Life SciencesBiochemistryCell BiologyBiophotonicsCell BiophysicsCellular MetabolismLaser-tissue InteractionOxidative MetabolismPhotochemistryReactive Oxygen SpeciesLaser PhotochemistryLasersSinglet Oxygen FormationSinglet Oxygen Generation
A qualirative E.P.R. (Electron Paramagnetic Resonance) study has been performed to determine the action of Low Level Lasers on living cells, Singlet oxygen (1O2) was found to be generated by Friend Erythroleukaemic Cells (FELC) after irradiating them with a HeNe laser. The production of 1O2 in the cell during irradiation was proved by an E.P.R. technique. No singlet oxygen is photoproduced by irradiating either cytochrome C or hemin.Singlet oxygen, in small amounts, is very significant in biochemical processes and hence can be important in biostimulation. It is proposed that singlet oxygen is photoproduced by the natural porphyrins in the cell.
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Detection of singlet oxygen production by ESR
Johan Moan, Einar Wold · Nature · 1979 · 314 citations
[Molecular mechanism of the therapeutic effect of low-intensity laser irradiation].
Singlet oxygen production by human eosinophils.
Jeffrey R. Kanofsky, Hans Hoogland, R. Wever et al. · Journal of Biological Chemistry · 1988 · 207 citations · Full text