Journal of the Marine Biological Association of the United Kingdom · 1962 · 18 citations · 14 references
Life SciencesMicrobiologyToxicologyEcotoxicologyMarine ToxicologyPhycologyAlgal ToxicologyCarcinogenicity AssessmentChemical CarcinogenesisEnvironmental CarcinogensHydrocarbon ToxicityRed AlgaeAromatic HydrocarbonsGrowth Rate IncreaseMarine Green AlgaeMechanisms Of CarcinogenicityPolycyclic Aromatic Hydrocarbon CarcinogenesisPolycyclic Aromatic Hydrocarbon ToxicityPolycyclic Aromatic HydrocarbonsRapid Screening Tests
Low concentrations of various carcinogenic polycyclic aromatic hydrocarbons cause a considerable increase in cell production when applied to sporelings of certain marine red algae. Whereas low concentrations of carcinogenic derivatives of benzanthracene stimulate cell production, similar concentrations of structurally related non-carcinogens inhibit it. The applicability of the method as a rapid screening test for carcinogens is discussed.
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Julian Huxley · The American Journal of the Medical Sciences · 1959 · 55 citations
Medicine, Cancer Biology, Oncology +12