SYNTHESIS OF NOVEL DERIVATIVES OF 2-CYANO-3-METHYLTHIO-3′-BENZYLAMINO ACRYLATES(ACRYLAMIDES) AND THEIR BIOLOGICAL ACTIVITY

Abstract

Abstract A series of new substituted derivatives of 2-cyano-3-methvlthio-3′-aminoacrylates(acrylamides) have been designed and synthesized. Their structures were confirmed by 1h NMR and elemental analysis. The bioassay test indicates that most of these new compounds show good Hill reaction inhibitory activity.